• PN: B111417


45x Ab-conjugated beads (S4P12 - human IL-32 Ab-bead). PN: B111417A. One vial containing 100 µL of anti-human IL-32 conjugated to AimPlex Bead S4P12

25x Biotin-detection Ab (human IL-32 Biotin-dAb). PN: B111417B. One vial containing 100 µL of biotinylated anti-human IL-32.

Lyophilized Standard Mix-Human Group 3 Panel B, 12-Plex. PN: HG3012B. One vial containing lyophilized recombinant human IL-9, IL-15, IL-16, IL-17C, IL-23p19, IL-24, IL-27, IL-31, IL-32, IL-34, OSM, and SCF.  Note: If multiple analyte kits on the above target list are ordered as a panel, only one vial of standard mix is supplied for those analyte kits.

STORAGE:  2-8 C in the dark.

IMPORTANT: Sodium azide forms explosive compounds with heavy metals. These products contain <0.05% (w/w) azide which with repeated contact with lead and copper commonly found in plumbing drains may result in the buildup of shock sensitive compounds. Dispose in accordance with regulations from your institute.

APPLICATION: Optimal antibody pair and antigen standard for assaying human IL-32.  Can be multiplexed with other analytes in Human Group 3.  To be used in conjunction with the AimPlex NR Basic Kit (PN: P100001) and a diluent kit. Refer to the AimPlex Multiplex Immunoassay User Manual and kit inserts for the assay procedure.

For Research Use Only.  Not for use in diagnostic procedures.

Assay Specifications:

Sample types: Cell culture supernatant, serum, plasma, bodily fluid and tissue/cell lysate

Sensitivity (LOD): < 10 pg/mL

Quantitation range:

LLOQ: < 20 pg/mL

ULOQ: > 5,000 pg/mL

Standard dose recovery: 70-130%

Intra-assay CV: < 10%

Inter-assay CV: < 20%

Cross-reactivity of analytes in Human Group 3: Negligible

Sample volume: 15 µL/test


Interleukin-31 (IL-31) is a cytokine with a four-helix bundle structure, which is preferentially produced by type 2 helper T cells (Th2). The structure of IL-31 places it in the IL-6 family of cytokines. IL-31 signals via a receptor complex that is composed of IL-31 receptor A (IL-31RA) and Oncostatin M receptor subunits. These receptor subunits are expressed in activated monocytes and in unstimulated epithelial cells. IL-31 is believed to play a role in inflammation of the skin.


1.      Kim SH, Han SY, Azam T, Yoon DY, Dinarello CA (January 2005). "Interleukin-32: a cytokine and inducer of TNFalpha". Immunity 22 (1): 131–42. doi:10.1016/j.immuni.2004.12.003. PMID 15664165.

2.      Identification of a novel gene expressed in activated natural killer cells and T cells. (PMID: 1729377) Dahl C.A. … Cairns J.S.(J. Immunol. 1992)

3.      BMP signaling coordinates gene expression and cell migration during precardiac mesoderm development. (PMID: 19913008) Christiaen L. … Levine M.(Dev. Biol. 2010)