- PN: B111357
45x Ab-conjugated beads (S5P5 - Human Activin A Ab-bead). PN: B111357A. One vial containing 100 µL of anti-human Activin A conjugated to AimPlex Bead S5P5.
25x Biotin-detection Ab (Human Activin A Biotin-dAb). PN: B111357B. One vial containing 100 µL of biotinylated anti-human EGF.
Lyophilized Standard Mix-Human Activin A. PN: B111357S. One vial containing lyophilized Activin A.
STORAGE: 2-8 C in the dark.
IMPORTANT: Sodium azide forms explosive compounds with heavy metals. These products contain <0.05% (w/w) azide which with repeated contact with lead and copper commonly found in plumbing drains may result in the buildup of shock sensitive compounds. Dispose in accordance with regulations from your institute.
APPLICATION: Optimal antibody pair and antigen standard for assaying human Activin A. To be used in conjunction with the AimPlex NR Basic Kit (PN: P100001) and a diluent kit. Refer to the AimPlex Multiplex Immunoassay User Manual and kit inserts for the assay procedure.
For Research Use Only. Not for use in diagnostic procedures.
Sample types: Cell culture supernatant, serum, plasma, bodily fluid and tissue/cell lysate
Sensitivity (LOD): < 30 pg/mL
LLOQ: < 50 pg/mL
ULOQ: > 20,000 pg/mL
Standard dose recovery: 70-130%
Intra-assay CV: < 10%
Inter-assay CV: < 20%
Sample volume: 15 µL/test
Activin-A is a TGF-beta family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin-A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin-A can be neutralized by inhibins and by the diffusible TGF-beta antagonist, Follistatin.
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