- PN: B215489
45x Ab-conjugated beads (S4P8 - Mouse ANGPT-1 Ab-bead). PN: B215489A. One vial containing 100 µL of anti-mouse ANGPT-1 conjugated to AimPlex Bead S4P8.
25x Biotin-detection Ab (Mouse ANGPT-1 Biotin-dAb). PN: B215489B. One vial containing 100 µL of biotinylated anti-mouse ANGPT-1.
Lyophilized Standard Mix - Mouse ANGPT-1. PN: B215489S. One vial containing lyophilized recombinant mouse ANGPT-1.
IMPORTANT: Sodium azide forms explosive compounds with heavy metals. These products contain <0.05% (w/w) azide which with repeated contact with lead and copper commonly found in plumbing drains may result in the buildup of shock sensitive compounds. Dispose in accordance with regulations from your institute.
APPLICATION: Optimal antibody pair and antigen standard for assaying human Mouse ANGPT-1/Angiopoietin-1. To be used in conjunction with the AimPlex Mouse/Rat Basic Kit (PN: P200201) and a diluent kit. Refer to the AimPlex Multiplex Immunoassay User Manual and kit inserts for the assay procedure.
For Research Use Only. Not for use in diagnostic procedures.
Sample types: Cell culture supernatant, serum, plasma, bodily fluid and tissue/cell lysate
Sensitivity (LOD): < 10 pg/mL
LLOQ: < 20 pg/mL
ULOQ: > 5,000 pg/mL
Standard dose recovery: 70-130%
Intra-assay CV: < 10%
Inter-assay CV: < 20%
Sample volume: 15 µL/test
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin 1 has been shown to interact with TEK tyrosine kinase. Diseases associated with ANGPT1 include chorioangioma and lipodermatosclerosis.
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