- PN: B212325
45x Ab-conjugated beads (S5P8 - Mouse Eotaxin-2 Ab-bead). PN: B212325A. One vial containing 100 µL of anti-mouse Eotaxin-2 conjugated to AimPlex Bead S5P8.
25x Biotin-detection Ab (Mouse Eotaxin-2 Biotin-dAb). PN: B212325B. One vial containing 100 µL of biotinylated anti-mouse eotaxin-2.
Lyophilized Standard Mix - Mouse Eotaxin-2. PN: MEOT2AG. One vial containing lyophilized recombinant mouse Eotaxin-2.
IMPORTANT: Sodium azide forms explosive compounds with heavy metals. These products contain <0.05% (w/w) azide which with repeated contact with lead and copper commonly found in plumbing drains may result in the buildup of shock sensitive compounds. Dispose in accordance with regulations from your institute.
APPLICATION: Optimal antibody pair and antigen standard for assaying human Mouse CCL24/MPIF-2/Eotaxin-2. To be used in conjunction with the AimPlex Mouse/Rat Basic Kit (PN: P200201) and a diluent kit. Refer to the AimPlex Multiplex Immunoassay User Manual and kit inserts for the assay procedure.
For Research Use Only. Not for use in diagnostic procedures.
Sample types: Cell culture supernatant, serum, plasma, bodily fluid and tissue/cell lysate
Sensitivity (LOD): < 10 pg/mL
LLOQ: < 20 pg/mL
ULOQ: > 5,000 pg/mL
Standard dose recovery: 70-130%
Intra-assay CV: < 10%
Inter-assay CV: < 20%
Sample volume: 15 µL/test
Chemokine (C-C motif) ligand 24 (CCL24), also known as Myeloid Progenitor Inhibitory factor 2 (MPIF-2) or eosinophil chemotactic protein 2 (Eotaxin-2) and small inducible cytokine A2 (SYCA2), is a small cytokine belonging to the CC chemokine family. CCL24 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. This chemokine is strongly chemotactic for resting T lymphocytes and slightly chemotactic for neutrophils. Elevated levels of Eotaxin-2 have been seen in patients with aspirin-exacerbated respiratory disease such as asthma. People with lower plasma levels of Eotaxin-2 have not been showing tendency to develop aspirin inducible asthma.
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