45x Ab-conjugated beads (S4P9 - NHP beta-NGF Ab-bead). PN: B411085A. One vial containing 100 µL of anti-NHP beta-NGF conjugated to AimPlex Bead S4P9.
25x Biotin-detection Ab (NHP beta-NGF Biotin-dAb). PN: B411085B. One vial containing 100 µL of biotinylated anti-NHP beta-NGF.
Lyophilized Standard - NHP beta-NGF. PN: B411085S. One vial containing lyophilized recombinant beta-NGF.
STORAGE: 2-8 C in the dark.
IMPORTANT: Sodium azide forms explosive compounds with heavy metals. These products contain <0.05% (w/w) azide which with repeated contact with lead and copper commonly found in plumbing drains may result in the buildup of shock sensitive compounds. Dispose in accordance with regulations from your institute.
APPLICATION: Optimal antibody pair and antigen standard for assaying NHP β-NGF/NGFB. To be used in conjunction with the AimPlex NR Basic Kit (PN: P100001) and a diluent kit. Refer to the AimPlex Multiplex Immunoassay User Manual and kit inserts for the assay procedure.
For Research Use Only. Not for use in diagnostic procedures.
Sample types: Cell culture supernatant, serum, plasma, bodily fluid and tissue/cell lysate
Sensitivity (LOD): < 10 pg/mL
LLOQ: < 20 pg/mL
ULOQ: > 5,000 pg/mL
Standard dose recovery: 70-130%
Intra-assay CV: < 10%
Inter-assay CV: < 20%
Sample volume: 15 µL/test
Beta-Nerve Growth Factor (NGF-β or NGFB) is a neurotrophic factor related to BDNF, NT-3 and NT-4. NGF-β acts through its receptor β-NGFR, and is involved in the development and maintenance of the sensory and sympathetic nervous systems and is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cellsNGF-β also is also involved in the growth, differentiation and survival of B lymphocytes. Human, mouse and rat proteins show cross-reactivity. Diseases associated with NGF include neuropathy, hereditary sensory and autonomic, typeV and neuroschistosomiasis.
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